Gluten Sensitivity Profile CHANGE

Profile details

• Gluten Single IgE Allergen
• Gliadin Antibodies (IgG) (deamidated)
• Immunoglobulin A
• Tissue Transglutaminase IgA
• HLA Tissue Typing DQ2/DQ8

Code

GLUT

Sample Reqs

ABB

Turnaround

10 days

Special instructions

If IgA deficiency is identified, a reflex deamidated Gliadin IgG will be carried out to determine whether the patient is likely to have coeliac disease. Coeliac pathway:

1. Initial TTG IgA samples are received and tested
2. If TTG IgA is LOW <0.2 U/ml reflex testing for Total IgA will be undertaken
3. If Total IgA is LOW <0.1 g/L then reflex testing for deamidated Gliadin IgG test will be undertaken
4. If TTG IgA is HIGH >/= 10 U/ml then reflex testing for Endomysial IgA will be undertaken as a confirmatory test for first time positive samples.

Sample type guide

A

Lavender Vacutainer, EDTA anticoagulant, 4ml/6ml (6ml EDTA tubes are used for specific PCR assays)

B

Gold Vacutainer, SST/Gel anticoagulant, 5ml

Related specialties

• Immunology
• Allergy

Additional information

• Request forms
• Specimens: collection, packaging, transport, rejection criteria
• Discontinued tests